Chronic kidney disease demonstrated significantly increased and maintained inflammation in the early stages of wound healing.

<p>Representative immunofluorescent sections of wound edges stained with CD45 and DAPI in <b>A</b>) normal mice and <b>B</b>) chronic kidney disease mice at day 7. <b>C</b>) Utilizing Tissue Gnostics quantification technology, chronic kidney disease wounds demonstrated a significantly increased and maintained inflammation in the early stages of wound healing. (Arrows indicate wound edges, white dots indicate epidermis, and brackets indicate dermis) (* <i>p</i><0.05, ** <i>p</i><0.01) (Magnification ×200) (n = 6–8 mice/group).