Effects of hydrogen sulfide gas on in vitro growth and metabolism of <i>P. falciparum</i>.

<p><i>P. falciparum</i> was grown from a starting parasitemia of 0.5% in the presence of added saline (0.9%) and increasing doses of NaHS and GYY4137. After 48 hours, (a) parasitemia was enumerated and (b–d) concentration of H⁺ (pH), glucose (mM) and lactate (mM) in the culture media was quantified. Presented as dot plot of N = 5 cultures in each condition with mean (line)+S.E.M. Significant differences are denoted with asterisks (*) according to p-values of <0.05(*), <0.01 (**) and <0.001(***) as determined by one-way ANOVA with Tukey’s post hoc.