<p>Above: representative FISH images of sinonasal squamous cell carcinoma samples without <i>SOX2</i> amplification (A), <i>SOX2</i> low level amplification (B) and <i>SOX2</i> high level amplification (C). Below: representative immunohistochemical stains of weak nuclear SOX2 expression in case of wildtype <i>SOX2</i> (D) and strong nuclear SOX2 expression in case harbouring <i>SOX2</i> amplification (E).</p
<p>Above, <i>SOX2</i> amplification status of primary sinonasal tumors and corresponding lymph node ...
<p>The upper panels show SOX2 fluorescence (red channel) with characteristic nuclear staining patter...
<p>(A) HE staining of mice lung tissue containing metastasis. (B) HE staining of mice liver tissue c...
<p>LLA: <i>SOX2</i> low level amplification; HLA: <i>SOX2</i> high level amplification; WT: <i>SOX2<...
<p>(A–D) IHC images of SOX2-positve colorectal cancer tissues. Arrows indicate patches of strong SOX...
<p><i>SOX2-</i>amplified sinonasal tumors exhibited significantly higher SOX protein expression than...
Objectives The transcription factor SOX2 (3q26.3-q27) is an embryonic stem cell factor contributing ...
<p>A) shows a tumor sample with a high SOX2 expression using immunohistochemistry (in 4x and 40x mag...
Background: Oral and oropharyngeal squamous cell carcinomas (OSCC) are among the most common cancers...
The transcription factor SOX2 (3q26.3-q27) is an embryonic stem cell factor contributing to the indu...
Recently, SOX2 has been identified as a potential lineage-specific oncogene in lung squamous cell ca...
<p><b>A</b>) Immunohistochemical staining of Sox2 demonstrating representative nuclear basal epithel...
Recently, SOX2 has been identified as a potential lineage-specific oncogene in lung squamous cell ca...
<p>(A) Negative nuclear SOX2 staining in a moderately differentiated CRC. (B) Positive nuclear SOX2 ...
<p><b>A</b>. Representative immunohistochemistry images showing expression of SOX2 in osteosarcoma t...
<p>Above, <i>SOX2</i> amplification status of primary sinonasal tumors and corresponding lymph node ...
<p>The upper panels show SOX2 fluorescence (red channel) with characteristic nuclear staining patter...
<p>(A) HE staining of mice lung tissue containing metastasis. (B) HE staining of mice liver tissue c...
<p>LLA: <i>SOX2</i> low level amplification; HLA: <i>SOX2</i> high level amplification; WT: <i>SOX2<...
<p>(A–D) IHC images of SOX2-positve colorectal cancer tissues. Arrows indicate patches of strong SOX...
<p><i>SOX2-</i>amplified sinonasal tumors exhibited significantly higher SOX protein expression than...
Objectives The transcription factor SOX2 (3q26.3-q27) is an embryonic stem cell factor contributing ...
<p>A) shows a tumor sample with a high SOX2 expression using immunohistochemistry (in 4x and 40x mag...
Background: Oral and oropharyngeal squamous cell carcinomas (OSCC) are among the most common cancers...
The transcription factor SOX2 (3q26.3-q27) is an embryonic stem cell factor contributing to the indu...
Recently, SOX2 has been identified as a potential lineage-specific oncogene in lung squamous cell ca...
<p><b>A</b>) Immunohistochemical staining of Sox2 demonstrating representative nuclear basal epithel...
Recently, SOX2 has been identified as a potential lineage-specific oncogene in lung squamous cell ca...
<p>(A) Negative nuclear SOX2 staining in a moderately differentiated CRC. (B) Positive nuclear SOX2 ...
<p><b>A</b>. Representative immunohistochemistry images showing expression of SOX2 in osteosarcoma t...
<p>Above, <i>SOX2</i> amplification status of primary sinonasal tumors and corresponding lymph node ...
<p>The upper panels show SOX2 fluorescence (red channel) with characteristic nuclear staining patter...
<p>(A) HE staining of mice lung tissue containing metastasis. (B) HE staining of mice liver tissue c...