<p>Oxymorphone concentrations were clustered to CYP2D6 genotype activity groups PM, HZ/IM, EM and UM. Measures represent means with -SD. Comparison of genotype groups by repeated measures ANOVA, p = 0.004.</p
<p>Distribution of <i>active substances</i> metabolised by the CYP2D6 genotype according to study gr...
<p>Genotype combination distributions and tHcy plasma levels according to genotype combination in pa...
This study investigated the differences in the pharmacokinetics (PK) of dextromethorphan and desipra...
<p>Boxes represent 1<sup>st</sup> and 3<sup>rd</sup> quartile; whiskers the 5<sup>th</sup> and 95<su...
<p>Patients were allocated to CYP2D6 genotype groups. Data are presented as mean with -SD. Repeated ...
BACKGROUND AND PURPOSE: There is high interindividual variability in the activity of drug-metabolizi...
A method for simultaneous phenotyping and genotyping for CYP2D6 and CYP2C19 was tested. Six healthy ...
The impact of polymorphic cytochrome P450 CYP2D6 enzyme on oxycodone's metabolism and clinical effic...
<p>Mean plasma concentration-time profiles of hydroxybupropion after oral administration of 150 mg o...
<p><i>CYP2D6</i> genotypes, activity score and predicted phenotypes for samples included in pyrosequ...
Background : Genotypes of the drug-metabolizing enzyme CYP2D6 influence plasma levels of 25% ...
Sallustio, BC; Davies, BJL; Coller, JK; James, HM; Gillis, D. and Somogyi, AAhttp://apps.isiknowledg...
CYP2D6 is a human cytochrome P450 that is responsible for the metabolism of a large number of drugs ...
BACKGROUND AND PURPOSE: There is high interindividual variability in the activity of drug-metabolizi...
<p>Plasma concentrations of amlodipine were measured at the end of study. Circles and triangles rep...
<p>Distribution of <i>active substances</i> metabolised by the CYP2D6 genotype according to study gr...
<p>Genotype combination distributions and tHcy plasma levels according to genotype combination in pa...
This study investigated the differences in the pharmacokinetics (PK) of dextromethorphan and desipra...
<p>Boxes represent 1<sup>st</sup> and 3<sup>rd</sup> quartile; whiskers the 5<sup>th</sup> and 95<su...
<p>Patients were allocated to CYP2D6 genotype groups. Data are presented as mean with -SD. Repeated ...
BACKGROUND AND PURPOSE: There is high interindividual variability in the activity of drug-metabolizi...
A method for simultaneous phenotyping and genotyping for CYP2D6 and CYP2C19 was tested. Six healthy ...
The impact of polymorphic cytochrome P450 CYP2D6 enzyme on oxycodone's metabolism and clinical effic...
<p>Mean plasma concentration-time profiles of hydroxybupropion after oral administration of 150 mg o...
<p><i>CYP2D6</i> genotypes, activity score and predicted phenotypes for samples included in pyrosequ...
Background : Genotypes of the drug-metabolizing enzyme CYP2D6 influence plasma levels of 25% ...
Sallustio, BC; Davies, BJL; Coller, JK; James, HM; Gillis, D. and Somogyi, AAhttp://apps.isiknowledg...
CYP2D6 is a human cytochrome P450 that is responsible for the metabolism of a large number of drugs ...
BACKGROUND AND PURPOSE: There is high interindividual variability in the activity of drug-metabolizi...
<p>Plasma concentrations of amlodipine were measured at the end of study. Circles and triangles rep...
<p>Distribution of <i>active substances</i> metabolised by the CYP2D6 genotype according to study gr...
<p>Genotype combination distributions and tHcy plasma levels according to genotype combination in pa...
This study investigated the differences in the pharmacokinetics (PK) of dextromethorphan and desipra...
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