Overview of genes transcriptionally up-regulated in <i>Schistosoma japonicum</i> in response to <i>in vivo</i> exposure to praziquantel.

<p>Broad functions known to be important to schistosome biology, and specific example genes are presented. Responses were noted separately for male and female parasites, and were classified as either “Early Phase” representing time points 30 min and 4 h, or “Late Phase” representative of 12 h and 24 h, after administration of praziquantel. Up-regulation of genes was considered relative to pre-drug administration.