Morphine affects podocytes through K and M receptors.

<p><b>A.</b> Human podocytes were treated with agonists specifically for DOR (labeled as D), KOR (K), or MOR (M) for 24 h, and the cell lysates were collected for Western blots. <b>B–E.</b> Quantification of the expression of nephrin (<b>B</b>), synaptopodin (<b>C</b>), CD2AP (<b>D</b>), and podocin (<b>E</b>) in <b>A</b>, and the results (mean ± SD) represent three independent samples. * p<0.05 compared with control (CN).