<i>CACNA2D3</i> arrests cell cycle at G1/S checkpoint.

<p>(A) Representatives and summary of DNA content of cells detected by flow cytometry. The results are expressed as mean±SD of three independent experiments. *, <i>P</i><0.05, **, <i>P</i><0.01. (B) Representatives and summary of DNA content in CACNA2D3 silenced cells. Scramble siRNA was used as a control. **, <i>P</i><0.01. (C, D, E) Expression of proteins was detected in CACNA2D3 overexpressed cells (C, E) and silenced cells (D). GAPDH and tubulin were used as loading controls.