†<p>The mutation was also found in another blood sample of LS relapsed CRC patient.</p>††<p>One patient carried both –39 C>T and c.23 A<u>C</u>G>A<u>T</u>G.</p>‡<p>Three patients carried somatic mutations in both <i>hMLH1</i> and <i>hMSH2</i> genes; one patient carried germline mutations in both <i>hMLH1</i> and <i>hMSH2</i> genes.</p
Colorectal cancer (CRC) is common with 3% of cases associated with germline mutations in the mismatc...
SummaryGerm-line mutations in DNA mismatch–repair genes impart a markedly elevated cancer risk, ofte...
Lynch syndrome (Hereditary Non Polyposis Colorectal Cancer, HNPCC) is one of the most common heredit...
<p>The relationships between somatic mutation of <i>hMLH1/hMSH2</i> gene and clinicopathological fea...
<p>The relationships between germline mutation of <i>hMLH1/hMSH2</i> gene and clinicopathological fe...
*<p>DNA variant found in the relapse tumor of a LS CRC patient.</p>‡<p>The variants were detected in...
Research on hMLH1 and hMSH2 mutations tend to focus on Lynch syndrome (LS) and LS-like colorectal ca...
Research on hMLH1 and hMSH2 mutations tend to focus on Lynch syndrome (LS) and LS-like colorectal ca...
<p>Prevalence of <i>hMLH1</i> and <i>hMSH2</i> gene germline mutation in different exons.</p
The prevalence of pathological germline mutations in colorectal cancer has been widely studied, as g...
textabstractBackground and Aims Lynch Syndrome (LS) is caused by pathogenic germline variants in one...
mutations were identified in 16 % (13/81) of HCL patients and coexist with BRAFV600E mutations. CDK...
<div><p>Abstract</p><p>The prevalence of pathological germline mutations in colorectal cancer has be...
Colorectal cancer (CRC) is the third most common type of cancer globally. About 25% of CRC cases app...
Colorectal carcinoma (CRC) is one of the most prevalent malignancies in the Czech Republic. In gener...
Colorectal cancer (CRC) is common with 3% of cases associated with germline mutations in the mismatc...
SummaryGerm-line mutations in DNA mismatch–repair genes impart a markedly elevated cancer risk, ofte...
Lynch syndrome (Hereditary Non Polyposis Colorectal Cancer, HNPCC) is one of the most common heredit...
<p>The relationships between somatic mutation of <i>hMLH1/hMSH2</i> gene and clinicopathological fea...
<p>The relationships between germline mutation of <i>hMLH1/hMSH2</i> gene and clinicopathological fe...
*<p>DNA variant found in the relapse tumor of a LS CRC patient.</p>‡<p>The variants were detected in...
Research on hMLH1 and hMSH2 mutations tend to focus on Lynch syndrome (LS) and LS-like colorectal ca...
Research on hMLH1 and hMSH2 mutations tend to focus on Lynch syndrome (LS) and LS-like colorectal ca...
<p>Prevalence of <i>hMLH1</i> and <i>hMSH2</i> gene germline mutation in different exons.</p
The prevalence of pathological germline mutations in colorectal cancer has been widely studied, as g...
textabstractBackground and Aims Lynch Syndrome (LS) is caused by pathogenic germline variants in one...
mutations were identified in 16 % (13/81) of HCL patients and coexist with BRAFV600E mutations. CDK...
<div><p>Abstract</p><p>The prevalence of pathological germline mutations in colorectal cancer has be...
Colorectal cancer (CRC) is the third most common type of cancer globally. About 25% of CRC cases app...
Colorectal carcinoma (CRC) is one of the most prevalent malignancies in the Czech Republic. In gener...
Colorectal cancer (CRC) is common with 3% of cases associated with germline mutations in the mismatc...
SummaryGerm-line mutations in DNA mismatch–repair genes impart a markedly elevated cancer risk, ofte...
Lynch syndrome (Hereditary Non Polyposis Colorectal Cancer, HNPCC) is one of the most common heredit...