The majority of lung-derived hematopoietic cells expressing exogenous Stat5 that can be maintained for a prolonged period in culture are immature granulocytes.

Bone marrow-derived progenitor cells in end-stage lung disease patients

Gilpin, Sarah E
Lung, Kalvin
de Couto, Geoffrey T
Cypel, Marcelo
Sato, Masaaki
Singer, Lianne G
Keshavjee, Shaf
Waddell, Thomas K

March 2018

Abstract Background Chronic lung diseases are marked ...

Long Term Culture of the A549 Cancer Cell Line Promotes Multilamellar Body Formation and Differentiation towards an Alveolar Type II Pneumocyte Phenotype.

James Ross Cooper
Muhammad Bilal Abdullatif
Edward C Burnett
Karen E Kempsell
Franco Conforti
Howard Tolley
Jane E Collins
Donna E Davies

January 2016

Pulmonary research requires models that represent the physiology of alveolar epithelium but concerns...

Soluble Signals from Mechanically Disrupted Lung Tissue Induce Lung-Related Gene Expression in Bone Marrow-Derived Cells In Vitro

Field-Corbett, Ciara
O'Dea, Shirley

January 2007

Differentiation of bone marrow (BM)-derived cells into lung epithelial cells has been reported in vi...

Downregulation of exogenous Stat5a leads to clearance of excessive granulocytes in circulation and in the lung as well as restoration of a normal progenitor pool.

Wan-chi Lin (5654470)
Jeffrey W. Schmidt (309077)
Bradley A. Creamer (397521)
Aleata A. Triplett (397522)
Kay-Uwe Wagner (212189)

April 2013

A. Relative contribution of myeloblasts and immature and mature granulocytes among the total numb...

Gain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lung.

Wan-chi Lin
Jeffrey W Schmidt
Bradley A Creamer
Aleata A Triplett
Kay-uwe Wagner

The Signal Transducer and Activator of Transcription 5 (Stat5) plays a significant role in normal he...

Differential activation of functionally distinct stat5 proteins by il-5 and gm-csf during eosinophil and neutrophil differentiation from human cd34+ hematopoietic stem cells

Eric Caldenhoven
Thamar B. Van Dijk
Annelien Tijmensen
Jan A. M. Raaijmakers
Jan-willem J. Lammers
Leo Koenderman
Rolf P. De Groot

January 1998

Interleukin-5 (IL-5) and granulocyte macrophage-colony stimulating factor (GM-CSF) are important cyt...

STAT5 is required for long-term maintenance of normal and leukemic human stem/progenitor cells

Schepers, Hein,
Gosliga, Djoke van,
Wierenga, Albertus T.J.,
Eggen, Bart J.L.,
Schuringa, Jan Jacob,
Vellenga, Edo,

January 2007

The transcription factor STAT5 fulfills a distinct role in the hematopoietic system, but its precise...

HEMATOPOIESIS AND STEM CELLS Brief report

Phenotype Tracks Ltc-ic

October 2016

Phenotypic markers associated with hu-man hematopoietic stem cells (HSCs) were developed and validat...

Characterization of hematopoietic stem cells isolated from lung of C57BL/6 mice (7th day of the experiment).

Evgenii Germanovich Skurikhin (732619)
Olga Victorovna Pershina (732620)
Alena Mikhaylovna Reztsova (732621)
Natalia Nikolaevna Ermakova (732622)
Ekaterina Sergeevna Khmelevskaya (732623)
Vycheslav Andreevich Krupin (732624)
Inna Ernestovna Stepanova (732625)
Andrew Vladimirovich Artamonov (732626)
Andrew Alexandrovich Bekarev (732627)
Pavel Gennadjevich Madonov (732628)
Alexander Mikhaylovich Dygai (732629)

April 2015

The phenotype of cells from lung was studied according to the protocol for hematopoietic stem cel...

Differential Activation of Functionally Distinct STAT5 Proteins by IL-5 and GM-CSF During Eosinophil and Neutrophil Differentiation from Human CD34^+ Hematopoietic Stem Cells

Caldenhoven, Eric
Dijk, Thamar B. van
Tijmensen, Annelien
Raaijmakers, J.A.M.
Lammers, J.W.J.
Koenderman, L.
Groot, Rolf P. de

September 1998

Interleukin-5 (IL-5) and granulocyte macrophage-colony stimulating factor (GM-CSF) are important c...

Lung-derived exosome uptake into and epigenetic modulation of marrow progenitor/stem and differentiated cells

Jason M. Aliotta
Mandy Pereira
Edmund H. Sears
Mark S. Dooner
Sicheng Wen
Laura R. Goldberg
Peter J. Quesenberry

September 2015

Background: Our group has previously demonstrated that murine whole bone marrow cells (WBM) that int...

Excessive granulopoiesis is controlled by hyperactive Stat5 in a cell autonomous manner.

Wan-chi Lin (5654470)
Jeffrey W. Schmidt (309077)
Bradley A. Creamer (397521)
Aleata A. Triplett (397522)
Kay-Uwe Wagner (212189)

April 2013

A. Relative contribution of lymphocytes, monocytes, and granulocytes to the total number o...

Single-cell STAT5 signal transduction profiling in normal and leukemic stem and progenitor cell populations reveals highly distinct cytokine responses.

Lina Han
Albertus T J Wierenga
Marjan Rozenveld-Geugien
Kim van de Lande
Edo Vellenga
Jan Jacob Schuringa

BACKGROUND: Signal Transducer and Activator of Transcription 5 (STAT5) plays critical roles in norma...

Proliferation of dendritic cell progenitors in long term culture is not dependent on granulocyte macrophage-colony stimulating factor

Wilson, Heather
Ni, Keping
O'Neill, Helen

December 2015

A unique long term culture (LTC) system has been developed which supports the production of dendriti...

Single-Cell STAT5 Signal Transduction Profiling in Normal and Leukemic Stem and Progenitor Cell Populations Reveals Highly Distinct Cytokine Responses

Han, Lina
Wierenga, Albertus T. J.
Rozenveld-Geugien, Marjan
van de Lande, Kim
Vellenga, Edo
Schuringa, Jan Jacob

November 2009

Background: Signal Transducer and Activator of Transcription 5 (STAT5) plays critical roles in norma...

Bone marrow-derived progenitor cells in end-stage lung disease patients

Gilpin, Sarah E
Lung, Kalvin
de Couto, Geoffrey T
Cypel, Marcelo
Sato, Masaaki
Singer, Lianne G
Keshavjee, Shaf
Waddell, Thomas K

March 2018

Abstract Background Chronic lung diseases are marked ...

Long Term Culture of the A549 Cancer Cell Line Promotes Multilamellar Body Formation and Differentiation towards an Alveolar Type II Pneumocyte Phenotype.

James Ross Cooper
Muhammad Bilal Abdullatif
Edward C Burnett
Karen E Kempsell
Franco Conforti
Howard Tolley
Jane E Collins
Donna E Davies

January 2016

Pulmonary research requires models that represent the physiology of alveolar epithelium but concerns...

Soluble Signals from Mechanically Disrupted Lung Tissue Induce Lung-Related Gene Expression in Bone Marrow-Derived Cells In Vitro

Field-Corbett, Ciara
O'Dea, Shirley

January 2007

Differentiation of bone marrow (BM)-derived cells into lung epithelial cells has been reported in vi...

Downregulation of exogenous Stat5a leads to clearance of excessive granulocytes in circulation and in the lung as well as restoration of a normal progenitor pool.

Wan-chi Lin (5654470)
Jeffrey W. Schmidt (309077)
Bradley A. Creamer (397521)
Aleata A. Triplett (397522)
Kay-Uwe Wagner (212189)

April 2013

A. Relative contribution of myeloblasts and immature and mature granulocytes among the total numb...

Gain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lung.

Wan-chi Lin
Jeffrey W Schmidt
Bradley A Creamer
Aleata A Triplett
Kay-uwe Wagner

The Signal Transducer and Activator of Transcription 5 (Stat5) plays a significant role in normal he...

Differential activation of functionally distinct stat5 proteins by il-5 and gm-csf during eosinophil and neutrophil differentiation from human cd34+ hematopoietic stem cells

Eric Caldenhoven
Thamar B. Van Dijk
Annelien Tijmensen
Jan A. M. Raaijmakers
Jan-willem J. Lammers
Leo Koenderman
Rolf P. De Groot

January 1998

Interleukin-5 (IL-5) and granulocyte macrophage-colony stimulating factor (GM-CSF) are important cyt...

STAT5 is required for long-term maintenance of normal and leukemic human stem/progenitor cells

Schepers, Hein,
Gosliga, Djoke van,
Wierenga, Albertus T.J.,
Eggen, Bart J.L.,
Schuringa, Jan Jacob,
Vellenga, Edo,

January 2007

The transcription factor STAT5 fulfills a distinct role in the hematopoietic system, but its precise...

HEMATOPOIESIS AND STEM CELLS Brief report

Phenotype Tracks Ltc-ic

October 2016

Phenotypic markers associated with hu-man hematopoietic stem cells (HSCs) were developed and validat...

Characterization of hematopoietic stem cells isolated from lung of C57BL/6 mice (7th day of the experiment).

Evgenii Germanovich Skurikhin (732619)
Olga Victorovna Pershina (732620)
Alena Mikhaylovna Reztsova (732621)
Natalia Nikolaevna Ermakova (732622)
Ekaterina Sergeevna Khmelevskaya (732623)
Vycheslav Andreevich Krupin (732624)
Inna Ernestovna Stepanova (732625)
Andrew Vladimirovich Artamonov (732626)
Andrew Alexandrovich Bekarev (732627)
Pavel Gennadjevich Madonov (732628)
Alexander Mikhaylovich Dygai (732629)

April 2015

The phenotype of cells from lung was studied according to the protocol for hematopoietic stem cel...

Differential Activation of Functionally Distinct STAT5 Proteins by IL-5 and GM-CSF During Eosinophil and Neutrophil Differentiation from Human CD34^+ Hematopoietic Stem Cells

Caldenhoven, Eric
Dijk, Thamar B. van
Tijmensen, Annelien
Raaijmakers, J.A.M.
Lammers, J.W.J.
Koenderman, L.
Groot, Rolf P. de

September 1998

Interleukin-5 (IL-5) and granulocyte macrophage-colony stimulating factor (GM-CSF) are important c...

Lung-derived exosome uptake into and epigenetic modulation of marrow progenitor/stem and differentiated cells

Jason M. Aliotta
Mandy Pereira
Edmund H. Sears
Mark S. Dooner
Sicheng Wen
Laura R. Goldberg
Peter J. Quesenberry

September 2015

Background: Our group has previously demonstrated that murine whole bone marrow cells (WBM) that int...

Excessive granulopoiesis is controlled by hyperactive Stat5 in a cell autonomous manner.

Wan-chi Lin (5654470)
Jeffrey W. Schmidt (309077)
Bradley A. Creamer (397521)
Aleata A. Triplett (397522)
Kay-Uwe Wagner (212189)

April 2013

A. Relative contribution of lymphocytes, monocytes, and granulocytes to the total number o...

Single-cell STAT5 signal transduction profiling in normal and leukemic stem and progenitor cell populations reveals highly distinct cytokine responses.

Lina Han
Albertus T J Wierenga
Marjan Rozenveld-Geugien
Kim van de Lande
Edo Vellenga
Jan Jacob Schuringa

BACKGROUND: Signal Transducer and Activator of Transcription 5 (STAT5) plays critical roles in norma...

Proliferation of dendritic cell progenitors in long term culture is not dependent on granulocyte macrophage-colony stimulating factor

Wilson, Heather
Ni, Keping
O'Neill, Helen

December 2015

A unique long term culture (LTC) system has been developed which supports the production of dendriti...

Single-Cell STAT5 Signal Transduction Profiling in Normal and Leukemic Stem and Progenitor Cell Populations Reveals Highly Distinct Cytokine Responses

Han, Lina
Wierenga, Albertus T. J.
Rozenveld-Geugien, Marjan
van de Lande, Kim
Vellenga, Edo
Schuringa, Jan Jacob

November 2009

Background: Signal Transducer and Activator of Transcription 5 (STAT5) plays critical roles in norma...

Bone marrow-derived progenitor cells in end-stage lung disease patients

Gilpin, Sarah E
Lung, Kalvin
de Couto, Geoffrey T
Cypel, Marcelo
Sato, Masaaki
Singer, Lianne G
Keshavjee, Shaf
Waddell, Thomas K

March 2018

Abstract Background Chronic lung diseases are marked ...

Long Term Culture of the A549 Cancer Cell Line Promotes Multilamellar Body Formation and Differentiation towards an Alveolar Type II Pneumocyte Phenotype.

James Ross Cooper
Muhammad Bilal Abdullatif
Edward C Burnett
Karen E Kempsell
Franco Conforti
Howard Tolley
Jane E Collins
Donna E Davies

January 2016

Pulmonary research requires models that represent the physiology of alveolar epithelium but concerns...

Soluble Signals from Mechanically Disrupted Lung Tissue Induce Lung-Related Gene Expression in Bone Marrow-Derived Cells In Vitro

Field-Corbett, Ciara
O'Dea, Shirley

January 2007

Differentiation of bone marrow (BM)-derived cells into lung epithelial cells has been reported in vi...

The majority of lung-derived hematopoietic cells expressing exogenous Stat5 that can be maintained for a prolonged period in culture are immature granulocytes.

Abstract

Extracted data

The majority of lung-derived hematopoietic cells expressing exogenous Stat5 that can be maintained for a prolonged period in culture are immature granulocytes.

Abstract

Extracted data

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