NE variations in the prefrontal cortex following chronic, sub-chronic and acute stressors.

<p>Mean (± SEM) concentration of MHPG and NE in the prefrontal cortex of male (Panels A and B) and female mice (Panel C and D) that had not been stressed (control), exposed to an acute stressor (resident intruder paradigms for the two sexes), a subchronic-intermittent stressor (7 stress sessions over 21 days) followed by the resident-intruder paradigm on Day 22, or a chronic stressor (variable stressor exposure on each off 21 days) followed by the resident-intruder stressor. *p<.05 relative to nonstressed mice.