<p>Dogs were infected with <i>Leishmania infantum-chagasi</i> plus five pairs of <i>Lutzomyia longipalpis</i> salivary glands. PBMC were obtained at days zero, 90, 180 and 270 post infection re-stimulated <i>in vitro</i> with <i>Leishmania infantum-chagasi</i> and the supernatant collected after 48 and 72 hours for determination of IFN-γ (A) and IL-10 (B) by ELISA, respectively. (C) Spearman correlation between IFN-γ levels and parasite load at 240 days after infection.</p
Dogs are the main reservoir host for zoonotic visceral leishmaniasis caused by Leishmania infantum....
International audienceIn South America, visceral leishmaniasis is a zoonotic disease with severe evo...
Visceral leishmaniasis (VL) is characterized by loss of T-cell responsiveness and absence of Leishma...
There is limited information available on cytokine profiles in dogs with different degrees of diseas...
While the response to Leishmania spp. is well characterized in mice and humans, much less is known c...
Leishmania infantum infection in humans and dogs can evolve with a wide range of clinical presentati...
Canine leishmaniosis has a wide range of disease severity from mild (stage I), to severe (stages II–...
Canine leishmaniosis has a wide range of disease severity from mild (stage I), to severe (stages II-...
<div><p><i>Leishmania infantum</i> infection in humans and dogs can evolve with a wide range of clin...
The factors responsible for the clinical progress of visceral leishmaniasis (VL) in dogs have not be...
The aim of this study was to evaluate cytokine expression in 22 Leishmania infantum naturally infect...
Visceral Leishmaniasis (VL) is caused by intracellular parasites of the genus Leishmania that affect...
To elucidate the local tissue cytokine response of dogs infected with Leishmania chagasi, cytokine m...
In this study, we searched for a connection between Leishmania load and cytokine expression levels i...
<p>(A) IFN-γ was quantified at time zero and one month after each dose of rLdccys1. (B) IL-10 was qu...
Dogs are the main reservoir host for zoonotic visceral leishmaniasis caused by Leishmania infantum....
International audienceIn South America, visceral leishmaniasis is a zoonotic disease with severe evo...
Visceral leishmaniasis (VL) is characterized by loss of T-cell responsiveness and absence of Leishma...
There is limited information available on cytokine profiles in dogs with different degrees of diseas...
While the response to Leishmania spp. is well characterized in mice and humans, much less is known c...
Leishmania infantum infection in humans and dogs can evolve with a wide range of clinical presentati...
Canine leishmaniosis has a wide range of disease severity from mild (stage I), to severe (stages II–...
Canine leishmaniosis has a wide range of disease severity from mild (stage I), to severe (stages II-...
<div><p><i>Leishmania infantum</i> infection in humans and dogs can evolve with a wide range of clin...
The factors responsible for the clinical progress of visceral leishmaniasis (VL) in dogs have not be...
The aim of this study was to evaluate cytokine expression in 22 Leishmania infantum naturally infect...
Visceral Leishmaniasis (VL) is caused by intracellular parasites of the genus Leishmania that affect...
To elucidate the local tissue cytokine response of dogs infected with Leishmania chagasi, cytokine m...
In this study, we searched for a connection between Leishmania load and cytokine expression levels i...
<p>(A) IFN-γ was quantified at time zero and one month after each dose of rLdccys1. (B) IL-10 was qu...
Dogs are the main reservoir host for zoonotic visceral leishmaniasis caused by Leishmania infantum....
International audienceIn South America, visceral leishmaniasis is a zoonotic disease with severe evo...
Visceral leishmaniasis (VL) is characterized by loss of T-cell responsiveness and absence of Leishma...