Immunoglobulin isotype distribution.

<p>Immunoglobulin isotype distribution of antibodies secreted by plasmablasts reactive with Vi and O-9,12 antigen (ASC/10⁶ PBMC) in 25 volunteers immunized with the Vi capsular polysaccharide, and with O-9,12 antigen in 25 volunteers immunized with the <i>Salmonella</i> Typhi Ty21a vaccine. The dots represent results of individual vaccinees, and the lines the medians of the numbers of plasmablasts secreting specific antibodies of the IgA, IgG or IgM isotype on day 7 after vaccination.