Cytokines influence the level of IFN-α production by enriched pDC in a concentration dependent manner.

<p>IFN-α responses of CD172a⁺-sorted cells stimulated with CpG (10 µg/ml; grey line) or FMDV (MOI of 5 TCID₅₀/cell; black line) for 24 h in presence of cytokines at indicated concentration. After stimulation, supernatants were collected and IFN-α was measured by ELISA. The marker represents the mean value of 2 independent experiments with each condition performed in triplicate cultures. The error bar represents the standard deviation.