Gal-9 decreases splenic Th17 cells.
- Masahiro Moritoki (400972)
- Takeshi Kadowaki (121129)
- Toshiro Niki (121127)
- Daisuke Nakano (314646)
- Genichiro Soma (400973)
- Hirohito Mori (314652)
- Hideki Kobara (400974)
- Tsutomu Masaki (121136)
- Masakazu Kohno (400975)
- Mitsuomi Hirashima (68149)
Publication date
April 2013
DOIAbstract
<p>(<b>A</b>) Comparison of frequency of Tim-3<sup>+</sup> IL17A<sup>+</sup> Th17 between PBS-treated (n = 4) and Gal-9-treated (n = 4) mice (**, P<0.01). Representative data of flow cytometric profiles are shown. (<b>B</b>) Spleen cells of MRL/lpr mice do not release IL-17. Spleen cells from PBS-treated (n = 4) and Gal-9-treated (n = 4) mice were cultured for 6 h with or without PMA+ionomycin. (<b>C</b>) Negligible level of IL-17 in plasma of MRL/lpr mice. PBS-treated (n = 4) and Gal-9-treated (n = 4) mice.</p
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