Effects of Gal-9 on the level of total IgG and anti-dsDNA antibody.

<p>(<b>A</b>) Comparison of anti-dsDNA antibody levels at 8, 9, 11, and 12 weeks of age between PBS-treated (n = 7) and Gal-9-treated (n = 6) mice. Human Gal-9 and PBS were injected intraperitoneally into 8-week-old mice 3-times/week for 4 weeks. (*, P<0.05) (<b>B</b>) Comparison of anti-dsDNA antibody levels in 8- to 12-week-old PBS-treated (n = 7) and Gal-9-treated (n = 6) mice. (<b>C</b>) Comparison of total IgG levels between PBS-treated (n = 7) and Gal-9-treated (n = 8) mice at 12 weeks of age. Human Gal-9 and PBS were injected intraperitoneally into 8-week-old mice 3-times/week for 4 weeks. (NS, not significant) (<b>D</b>) Comparison of total IgG levels in 8- and 12-week-old PBS-treated (n = 7) and Gal-9-treated (n = 8) mice. (NS, not significant).