<p><i><b>A,</b></i> Graph showing the average startle response to either a 1000Hz stimulus at 146 dB or a tap stimulus of both mutants (<i>tm246a</i>: n = 9, <i>t20325</i>: n = 23) and their WT siblings (<i>tm246a</i>: n = 15, <i>t20325</i>: n = 19). <b><i>B,</i></b> Averaged traces of vestibular-induced eye movements from WT siblings (n = 11) and <i>tm246a</i> mutants (n = 12) over 60 sec. <b><i>C,</i></b> Average of peak amplitude of vestibular-induced eye movements at 0.25 Hz. Each dot represents one eye from an individual larva at 5 dpf (WT: n = <i>11, tm246a:</i> n = 12). A Mann-Whitney U-test was used to compare differences between mutants and WT siblings.</p
<p>(<b>A</b>) Average ABR waveforms at 16 kHz for wild-type (WT) (purple, n = 6) and <i>Npr2</i> mut...
<p>(A) Immunohistochemical staining of inner ear sections showed reduced SLC12A2 expression (brown) ...
<p><b>A</b>. Example traces showing stimulus evoked EJPs and spontaneous mEJPs. <b>B-C.</b> mEJP amp...
<p>(<b>A</b>)Representative ABR thresholds (with click) from wild-type B6 (right panel) and mutant <...
<p><i><b>A–C,</b></i> FM 1-43 label of neuromast HCs in WT, <i>tm246a</i> and <i>t20325</i> mutants ...
<p><b>A.</b> Compared with C57BL/6 wild-type (gray bar, n = 14) and fGluN1 (Flox) controls (while ba...
Examples of three mutant mouse lines with altered ABR waveforms are shown. ABR thresholds are plotte...
The purpose of this research was to identify vestibular deficits in mice using linear vestibular evo...
New mutant mouse lines with hearing impairment categorised as Severe–Profound (A), High frequency (B...
The purpose of this research was to identify vestibular deficits in mice using linear vestibular evo...
Several new mutant lines showed normal or near-normal ABR thresholds at young ages followed by progr...
<p><b>A</b>. Example stimulus evoked EJPs and spontaneous mEJPs. <b>B-C.</b> The amplitude (B) and f...
<p>OKR is plotted at several time points before and after dark treatment for 45 min. WT sibling larv...
<p>A) At 5 dpf, WT and <i>zvm7<sup>w65</sup></i> responses are similar. B) At 6 dpf, <i>zvm7<sup>w65...
<p>(*average of 500, 1000, and 2000 Hz)</p><p>(†average of 250, 500, 1000 Hz)</p><p><i>GJB2</i> muta...
<p>(<b>A</b>) Average ABR waveforms at 16 kHz for wild-type (WT) (purple, n = 6) and <i>Npr2</i> mut...
<p>(A) Immunohistochemical staining of inner ear sections showed reduced SLC12A2 expression (brown) ...
<p><b>A</b>. Example traces showing stimulus evoked EJPs and spontaneous mEJPs. <b>B-C.</b> mEJP amp...
<p>(<b>A</b>)Representative ABR thresholds (with click) from wild-type B6 (right panel) and mutant <...
<p><i><b>A–C,</b></i> FM 1-43 label of neuromast HCs in WT, <i>tm246a</i> and <i>t20325</i> mutants ...
<p><b>A.</b> Compared with C57BL/6 wild-type (gray bar, n = 14) and fGluN1 (Flox) controls (while ba...
Examples of three mutant mouse lines with altered ABR waveforms are shown. ABR thresholds are plotte...
The purpose of this research was to identify vestibular deficits in mice using linear vestibular evo...
New mutant mouse lines with hearing impairment categorised as Severe–Profound (A), High frequency (B...
The purpose of this research was to identify vestibular deficits in mice using linear vestibular evo...
Several new mutant lines showed normal or near-normal ABR thresholds at young ages followed by progr...
<p><b>A</b>. Example stimulus evoked EJPs and spontaneous mEJPs. <b>B-C.</b> The amplitude (B) and f...
<p>OKR is plotted at several time points before and after dark treatment for 45 min. WT sibling larv...
<p>A) At 5 dpf, WT and <i>zvm7<sup>w65</sup></i> responses are similar. B) At 6 dpf, <i>zvm7<sup>w65...
<p>(*average of 500, 1000, and 2000 Hz)</p><p>(†average of 250, 500, 1000 Hz)</p><p><i>GJB2</i> muta...
<p>(<b>A</b>) Average ABR waveforms at 16 kHz for wild-type (WT) (purple, n = 6) and <i>Npr2</i> mut...
<p>(A) Immunohistochemical staining of inner ear sections showed reduced SLC12A2 expression (brown) ...
<p><b>A</b>. Example traces showing stimulus evoked EJPs and spontaneous mEJPs. <b>B-C.</b> mEJP amp...