FTY720-P enhanced BDNF production.
- Yukiko Doi (217308)
- Hideyuki Takeuchi (217302)
- Hiroshi Horiuchi (190839)
- Taketo Hanyu (402194)
- Jun Kawanokuchi (217331)
- Shijie Jin (217310)
- Bijay Parajuli (217329)
- Yoshifumi Sonobe (217333)
- Tetsuya Mizuno (217344)
- Akio Suzumura (48930)
Publication date
April 2013
DOIAbstract
<p>(A) qRT-PCR data for neurotrophic factors in neurons. FTY720-P significantly upregulated mRNA expression levels of BDNF. *, <i>P</i><0.05. Values are means ± SEM (n = 6). (B) Western blotting data for BDNF production. FTY720-P significantly enhanced neuronal BDNF production. BDNF levels are quantified relative to those in untreated neurons. NT, no treatment. *, <i>P</i><0.05. Values are means ± SEM (n = 6). (C) ELISA data for BDNF production. BDNF levels significantly increased in response to FTY720-P. NT, no treatment. †, <i>P</i><0.001. Values are means ± SEM (n = 3).</p
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