<p>We discovered that mutations in <em>Nle1</em>, a gene that is implicated in the Notch pathway in <em>Drosophila</em>, leads to misregulation of several <em>Wnt</em> family members, but not <em>Notch</em> target genes, in mouse embryos.</p
The Notch signaling pathway is an evolutionarily conserved signaling mechanism and mutations in its ...
Canonical Wnt signaling, below the Fz/LRP receptor complex, induces the stabilization of β-catenin v...
Awd, the Drosophila homologue of NME1/2 metastasis suppressors, plays key roles in many signaling pa...
In order to determine the genetic pathways required for early mammalian fetal development, a positio...
The Notch gene of Drosophila encodes a large transmembrane protein involved in cell fate determinati...
Wnts are evolutionarily conserved signaling ligands critical for animal development. Genetic enginee...
A remarkable interdisciplinary effort has unraveled the WNT (Wingless and INT-1) signal transduction...
The development of tissues and organs in embryos is controlled by an interplay of several signaling ...
International audienceNotch signaling is an evolutionarily conserved pathway involved in intercellul...
The Wnt-Wingless (Wg) pathway is one of a core set of evolutionarily conserved signaling pathways th...
Signaling molecules play essential roles in communication between cells. Wnt signaling molecules ar...
AbstractRecent genetic studies in Drosophila and mouse have uncovered a new aspect of the Wnt signal...
In the developing Drosophila central nervous system (CNS), neural progenitor (neuroblast [NB]) selec...
AbstractThe Notch pathway plays a key role in the formation of many tissues and cell types in Metazo...
<div><p>The <i>Notch</i> gene encodes an evolutionarily conserved cell surface receptor that generat...
The Notch signaling pathway is an evolutionarily conserved signaling mechanism and mutations in its ...
Canonical Wnt signaling, below the Fz/LRP receptor complex, induces the stabilization of β-catenin v...
Awd, the Drosophila homologue of NME1/2 metastasis suppressors, plays key roles in many signaling pa...
In order to determine the genetic pathways required for early mammalian fetal development, a positio...
The Notch gene of Drosophila encodes a large transmembrane protein involved in cell fate determinati...
Wnts are evolutionarily conserved signaling ligands critical for animal development. Genetic enginee...
A remarkable interdisciplinary effort has unraveled the WNT (Wingless and INT-1) signal transduction...
The development of tissues and organs in embryos is controlled by an interplay of several signaling ...
International audienceNotch signaling is an evolutionarily conserved pathway involved in intercellul...
The Wnt-Wingless (Wg) pathway is one of a core set of evolutionarily conserved signaling pathways th...
Signaling molecules play essential roles in communication between cells. Wnt signaling molecules ar...
AbstractRecent genetic studies in Drosophila and mouse have uncovered a new aspect of the Wnt signal...
In the developing Drosophila central nervous system (CNS), neural progenitor (neuroblast [NB]) selec...
AbstractThe Notch pathway plays a key role in the formation of many tissues and cell types in Metazo...
<div><p>The <i>Notch</i> gene encodes an evolutionarily conserved cell surface receptor that generat...
The Notch signaling pathway is an evolutionarily conserved signaling mechanism and mutations in its ...
Canonical Wnt signaling, below the Fz/LRP receptor complex, induces the stabilization of β-catenin v...
Awd, the Drosophila homologue of NME1/2 metastasis suppressors, plays key roles in many signaling pa...