In vivo migration profile of cultured DCs.

<p><b>(A)–(C)</b> Bioluminescent imaging of rats positioned dorsally (left panels) and ventrally (right panels) 6 h post-tMCAO and 3 h post-infusion of: <b>(A)</b> vehicle, <b>(B)</b> 2×10⁶ luciferase-DCs, or <b>(C)</b> 4×10⁶ luciferase-DCs <b>(D)</b> High resolution (low-binning) image of a luciferase-DC-infused rat at the same time point as (A)–(C). <b>(E)</b> In vivo tracking of radiolabeled DCs with SPECT. Representative images of 3 rats infused with radiolabeled DCs 3 h post-tMCAO and imaged by SPECT at 5–20 min and again at 2.5–6 h post-DC infusion. Inset in top left panel indicates the orientation of rats during imaging. Rat number (1–3) and imaging time post-DC infusion are indicated at the bottom of each image panel.