Analysis of CEACAM/PSG family gene evolution based on the Maximum Likelihood method.

<p><b>a)</b> Phylogenetic tree of PSG subfamily genes from human, chimpanzee, and Rhesus monkey. A Rhesus monkey-specific cluster and an ape-specific cluster are indicated by vertical bars on the right. Potential pseudogenes, including human PSG10, chimpanzee LOC468901, and Rhesus monkey LOC709992, were excluded from the analysis. Human, Hsa; Chimpanzee, Ptr; Rhesus monkey, Mmu. <b>b)</b> Phylogenetic tree of 48 CEACAM family proteins from human, dog (<i>C. familiaris</i>), opossum (<i>M. domestica</i>), and platypus (<i>O. anatinus</i>). The analysis involved 48 protein sequences. The human CEACAM1-like cluster is indicated by a vertical bar on the right. Human, Hsa; dog, Cfa, opossum, Mdo; platypus, Oan. <b>c)</b> Phylogenetic tree of teleost CEACAM homologs. Twenty-three CEACAM proteins from <i>D. rerio</i>, <i>G. aculeatus</i>, <i>T. rubripes</i>, and <i>T. nigroviridis</i> were analyzed. A <i>D. rerio</i>-specific cluster is indicated by a vertical bar on the right.