<p>Aid-cre-cd2 line 1 and dME-ac-cre line 1 mice (12 weeks of age) were immunized with SRBC and sacrificed on day 7 after immunization. The percentage of hCD2+ and RFP+ cells among B cells or germinal-center (GC) B cells is indicated. SPL, spleen. FACS results are representative of two independent experiments.</p
<p>A. Brightfield microscopy of representative spleen sections from day 9 and 30 sRBC immunized WT a...
<p>8 week old <i>Ret</i> conditional knockout <i>hCD2</i>Cre<sup>/</sup><i>Ret<sup>null/fl</sup></i>...
<p>Distribution of CD45.1+ and CD45.2+ cells in the spleen of recipient mice 3 months after bone mar...
<p>FACS analysis of hCD2 and RFP expression in naïve CD3+ or CD4+CD3+ T cells isolated from (A) sple...
<p>(A) Representative sorting and gating strategies for samples from the germinal centers of Peyeŕs ...
<p>RFP and hCD2 in B cells (B220+) or germinal-center (GC) B cells (B220+CD38–) in Peyer’s Patches (...
<p>(A) Diagrammatic representation of experiment protocol. BALB/c mice were immunized with SRBC on d...
<p>(<b>A</b>) IHC images of PNA (dark blue) vs B220 (brown) expression in spleen sections of WT and ...
<p>(<b>A</b>) Immunohistochemical (IHC) images of PNA (dark blue) vs B220 (brown) expression in sple...
<p>BALB/c and <i>Cr2<sup>−/−</sup></i> mice were irradiated and reconstituted with either BALB/c or ...
<p>(<b>A</b>) Flow cytometry analysis of the percentage and number of PD-1<sup>+</sup>CXCR5<sup>+</s...
<p>All animals were crossed with rosa-tdRFP.</p><p>Three mice from each line were analyzed.</p><p>Pe...
<p>(A) A schematic view of SRBC immunization and anti-CD40L-TM treatment protocol: a cohort of BALB/...
<p>Thymus and spleens from 5–6 week old naïve WT and HK2 KO animals were isolated. (A) Representativ...
<p>(a) GC formation in the spleen in response to PBS or sheep erythrocyte (SRBC) immunization examin...
<p>A. Brightfield microscopy of representative spleen sections from day 9 and 30 sRBC immunized WT a...
<p>8 week old <i>Ret</i> conditional knockout <i>hCD2</i>Cre<sup>/</sup><i>Ret<sup>null/fl</sup></i>...
<p>Distribution of CD45.1+ and CD45.2+ cells in the spleen of recipient mice 3 months after bone mar...
<p>FACS analysis of hCD2 and RFP expression in naïve CD3+ or CD4+CD3+ T cells isolated from (A) sple...
<p>(A) Representative sorting and gating strategies for samples from the germinal centers of Peyeŕs ...
<p>RFP and hCD2 in B cells (B220+) or germinal-center (GC) B cells (B220+CD38–) in Peyer’s Patches (...
<p>(A) Diagrammatic representation of experiment protocol. BALB/c mice were immunized with SRBC on d...
<p>(<b>A</b>) IHC images of PNA (dark blue) vs B220 (brown) expression in spleen sections of WT and ...
<p>(<b>A</b>) Immunohistochemical (IHC) images of PNA (dark blue) vs B220 (brown) expression in sple...
<p>BALB/c and <i>Cr2<sup>−/−</sup></i> mice were irradiated and reconstituted with either BALB/c or ...
<p>(<b>A</b>) Flow cytometry analysis of the percentage and number of PD-1<sup>+</sup>CXCR5<sup>+</s...
<p>All animals were crossed with rosa-tdRFP.</p><p>Three mice from each line were analyzed.</p><p>Pe...
<p>(A) A schematic view of SRBC immunization and anti-CD40L-TM treatment protocol: a cohort of BALB/...
<p>Thymus and spleens from 5–6 week old naïve WT and HK2 KO animals were isolated. (A) Representativ...
<p>(a) GC formation in the spleen in response to PBS or sheep erythrocyte (SRBC) immunization examin...
<p>A. Brightfield microscopy of representative spleen sections from day 9 and 30 sRBC immunized WT a...
<p>8 week old <i>Ret</i> conditional knockout <i>hCD2</i>Cre<sup>/</sup><i>Ret<sup>null/fl</sup></i>...
<p>Distribution of CD45.1+ and CD45.2+ cells in the spleen of recipient mice 3 months after bone mar...