<p>Linear regression analysis of log- transformed apparent volume of distribution for BALB/c mice, New Zealand white Hra: (NZW) SPF albino rabbits, cynomolgus monkeys and beagle dogs versus log-transformed corresponding animal body weight, following oral (gavage) administration of ST-246 by gavage at a dose of 2000, 100, 100 and 30 mg/kg, respectively.</p
<p>Number of mice appears in brackets. Data are represented as mean ± SEM. Different letters within ...
<p>SOI, start of infusion.</p><p>IV, intravenous.</p><p>PO, per oral.</p><p>BID, twice a day.</p
The authors talk about the confounding effects of gavage in mice. He said that gavage is the most wi...
<p>Linear regression analysis of log-transformed plasma clearance for BALB/c mice, New Zealand white...
<p>Linear regression analysis of log-transformed plasma clearance multiplied by corresponding maximu...
<p>♀ & φ = Values from simple allometry.</p><p>Φ = Values from MLP-corrected allometry.</p
<p>Plasma pharmacokinetic estimates for BALB/c mice, New Zealand white Hra: (NZW) SPF albino rabbits...
Plasma pharmacokinetics of ST-246, smallpox therapeutic, was evaluated in mice, rabbits, monkeys and...
<p>Concentration-time curve for C16 on dosing via oral gavage at 300 mg/kg in the mouse.</p
<p>Plasma concentration of ST-246 after a single oral dose of 3 (chartreuse hexagons), 10 (purple sq...
<p>Log dose vs. oral bioavailability among mice (●), rats (■), and dogs (▲) showing the maximum exte...
The authors talk about the confounding effects of gavage in mice. He said that gavage is the most wi...
The authors talk about the confounding effects of gavage in mice. He said that gavage is the most wi...
The authors talk about the confounding effects of gavage in mice. He said that gavage is the most wi...
<p>Three mice were bled and sacrificed at each point. Bars represent the standard deviation.</p
<p>Number of mice appears in brackets. Data are represented as mean ± SEM. Different letters within ...
<p>SOI, start of infusion.</p><p>IV, intravenous.</p><p>PO, per oral.</p><p>BID, twice a day.</p
The authors talk about the confounding effects of gavage in mice. He said that gavage is the most wi...
<p>Linear regression analysis of log-transformed plasma clearance for BALB/c mice, New Zealand white...
<p>Linear regression analysis of log-transformed plasma clearance multiplied by corresponding maximu...
<p>♀ & φ = Values from simple allometry.</p><p>Φ = Values from MLP-corrected allometry.</p
<p>Plasma pharmacokinetic estimates for BALB/c mice, New Zealand white Hra: (NZW) SPF albino rabbits...
Plasma pharmacokinetics of ST-246, smallpox therapeutic, was evaluated in mice, rabbits, monkeys and...
<p>Concentration-time curve for C16 on dosing via oral gavage at 300 mg/kg in the mouse.</p
<p>Plasma concentration of ST-246 after a single oral dose of 3 (chartreuse hexagons), 10 (purple sq...
<p>Log dose vs. oral bioavailability among mice (●), rats (■), and dogs (▲) showing the maximum exte...
The authors talk about the confounding effects of gavage in mice. He said that gavage is the most wi...
The authors talk about the confounding effects of gavage in mice. He said that gavage is the most wi...
The authors talk about the confounding effects of gavage in mice. He said that gavage is the most wi...
<p>Three mice were bled and sacrificed at each point. Bars represent the standard deviation.</p
<p>Number of mice appears in brackets. Data are represented as mean ± SEM. Different letters within ...
<p>SOI, start of infusion.</p><p>IV, intravenous.</p><p>PO, per oral.</p><p>BID, twice a day.</p
The authors talk about the confounding effects of gavage in mice. He said that gavage is the most wi...