Replication of vertically transmitted RSV.

<p><i>(</i><b><i>A</i></b><i>)</i> Fluorescence-activated sorting of fetal cells from dams infected with rrRSV or pathogen-free control dams. Each curve has a different computer-generated color corresponding to a different fetus. RFP was detected in two-thirds of the fetuses harvested from dams infected with rrRSV, whereas the other third overlapped the control fetuses harvested from pathogen-free dams. <i>(</i><b><i>B</i></b><i>)</i> Geometric mean fluorescent intensity (MFI) averaged from the same flow cytometry measurements confirmed a significant increase in red fluorescence in fetuses from rrRSV- infected dams. * = p<0.05 compared to control fetuses from pathogen-free dams. <i>(</i><b><i>C</i></b><i>)</i> FACS analysis showed that exposure to rrRSV <i>in utero</i> was associated to fetal overexpression of NGF protein.