<p>Cellular growth rate as a function of the plasmid copy number (following <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1003036#pcbi.1003036.e014" target="_blank">Equation 1</a>), with , , and . The copy number , which is optimal for cell growth, is denoted by the vertical dashed line.</p
<p>(a,b) protein concentration peak fold-increase <i>R</i> and width <i>T</i><sub><i>p</i></sub> as ...
<p>ND: Not done,</p>*<p>The number shown is the plasmid copy number determined plus 1 (genomic copy)...
Many autonomously replicating genetic elements exist as multiple copies within the cell. The copy nu...
<p>(A) Number of plasmid copies per cell and (B) plasmid concentration (open circles) and RNA I conc...
<p>a. Estimated from <i>M</i><sub>C</sub> using <i>V</i> = <i>c</i>×<i>M</i><sub>C</sub>, based on t...
<p>(A) Growth-rate dependence of the number of RNA I molecules per plasmid (open circles) and the ra...
The segregation distribution depends on the number of plasmids in the mother cell.</p
<p>The effects of obedience (increasing copy number control ) on the distribution of plasmid copy nu...
Copy number (plasmids/cell) and growth rate (mOD600/min) data collected from the same clones isolate...
Genetic circuits in bacteria are intimately coupled to the cellular growth rate as many parameters o...
<p>Stable (solid) and unstable (dashed) equilibrium copy numbers for a single cell as a function of...
Plasmids with the 2 μ plasmid origin are commonly-used in the genetic engineering of the budding ye...
<p>Each curve represents the deterministic relationship between the number of plasmids at the begin...
<p>*Weight/copy was calculated using Geneious (v.8.1.3) which considers the exact sequence of the pl...
<p>Growth and copy number of plasmids in the gTOW experiment with various leucine concentrations are...
<p>(a,b) protein concentration peak fold-increase <i>R</i> and width <i>T</i><sub><i>p</i></sub> as ...
<p>ND: Not done,</p>*<p>The number shown is the plasmid copy number determined plus 1 (genomic copy)...
Many autonomously replicating genetic elements exist as multiple copies within the cell. The copy nu...
<p>(A) Number of plasmid copies per cell and (B) plasmid concentration (open circles) and RNA I conc...
<p>a. Estimated from <i>M</i><sub>C</sub> using <i>V</i> = <i>c</i>×<i>M</i><sub>C</sub>, based on t...
<p>(A) Growth-rate dependence of the number of RNA I molecules per plasmid (open circles) and the ra...
The segregation distribution depends on the number of plasmids in the mother cell.</p
<p>The effects of obedience (increasing copy number control ) on the distribution of plasmid copy nu...
Copy number (plasmids/cell) and growth rate (mOD600/min) data collected from the same clones isolate...
Genetic circuits in bacteria are intimately coupled to the cellular growth rate as many parameters o...
<p>Stable (solid) and unstable (dashed) equilibrium copy numbers for a single cell as a function of...
Plasmids with the 2 μ plasmid origin are commonly-used in the genetic engineering of the budding ye...
<p>Each curve represents the deterministic relationship between the number of plasmids at the begin...
<p>*Weight/copy was calculated using Geneious (v.8.1.3) which considers the exact sequence of the pl...
<p>Growth and copy number of plasmids in the gTOW experiment with various leucine concentrations are...
<p>(a,b) protein concentration peak fold-increase <i>R</i> and width <i>T</i><sub><i>p</i></sub> as ...
<p>ND: Not done,</p>*<p>The number shown is the plasmid copy number determined plus 1 (genomic copy)...
Many autonomously replicating genetic elements exist as multiple copies within the cell. The copy nu...