Representative photomicrographs of strain-specific differences in the expression of NE markers in prostate tumors from TRAMP F1 mice.

<p>Panels (a), (b) and (c) show H&E staining of the tumors; Panels (d), (e) and (f) show IHC staining of tumors with NE marker synaptophysin; Panels (g), (h) and (i) show IHC staining with FOXA1; Panels (j), (k) and (l) show IHC staining with FOXA2. Arrows point to normal prostate luminal cells, showing positive staining for FOXA1 and no staining for the NE markers, synaptophysin and FOXA2. Bar denotes 100 µm.