Expression patterns of the enzymes responsible for the catabolism of Phe and Tyr.

<p>Protein expressions of PAH, HPD, HGD, and FAH in the livers of pigs, rats, mice, and male (♂, <b>A</b>) bats were determined by Western blotting. H and A indicate bats in hibernation and active states, respectively. Arrow heads indicate predicted molecular weight (kDa) of the proteins; the numbers in parentheses denote observed molecular weights. (<b>B</b>) Relative protein levels (y-axis) are represented as mean ± SD. The lowest level of a detectable protein is considered as 1. Hibernation (H) and active (A) states are represented by light-gray and black bars, respectively. Phylogenetic trees are drawn at the bottom of the panel. Statistical significance: *<i>P</i><0.05, **<i>P</i><0.001.