Adipose tissue lipid metabolism gene expression.

<p>Retroperirenal adipose tissue mRNA gene expression for genes involved in lipid metabolism in Ctl (circle and dotted line) and C5L2^−/− (square and solid line) mice on chow diet (white circle or square) and DIO (black circle or square). Adipogenesis-related genes (A–B); triglyceride synthesis-related genes (C–D); cell membrane fatty acid transport-related genes (E–F); thermogenesis-related genes (G–H) and mitochondrial long chain fatty acid transport-related genes (I). Data are expressed as relative expression (re) mean±SEM (n = 4–5 mice per group) compared to 6 weeks chow diet Ctl set as 1 where two-way (2-way) ANOVA for genotype × time between Ctl and C5L2^−/− for each diet or adipose tissue with a Bonferroni post-test where * <i>p</i><0.05, ** <i>p</i><0.01 and *** <i>p</i><0.001 for C5L2^−/− vs. Ctl. Abbreviations: CEBPA, CCAAT/enhancer-binding protein α; PPARG, peroxisome proliferator-activated receptor γ; DGAT1 and 2, diacylglycerol O- acyltransferase 1 and 2; FABP3, fatty acid binding protein 3; CD36 or FAT, fatty acid transporter; UCP1 and 3, uncoupling protein 1 and 3; CPT1B, carnitine palmitoyltransferase 1B.