Experiment 1, mouse wheel running.

<p>Average daily distance ran for the baseline, injection, and recovery week for animals treated with saline, Vivo-morpholino vehicle only (scramble) and the Vivo-morpholino targeting <i>Vmat2</i> (Vmat2). Vmat2 group significantly (*p = 0.001) increased activity in the recovery week compared to the baseline and injection week. There was no difference in physical activity (p>0.05) in the scramble or saline treated animals for baseline, injection, and recovery weeks.