<p>(A) Simultaneous detection of PC and choline peaks in MCF7 cell cytosolic preparations over 1 hour; (B) Time courses of PC production in control and SAHA-treated cells in representative experiments, showing increased choline kinase activity with treatment.</p
Phosphatidylcholine metabolism was investigated in Nb 2 node rat lymphoma, a cell line which is depe...
The glycerophospholipid phosphatidylcholine is the most abundant phospholipid species of eukaryotic ...
We studied the effect of choline depletion on the biosynthesis of phosphatidylcholine (PC) and the d...
<p>HEK293T cells were transfected with eukaryotic expression vectors of human ChoKα1 and ChoKβ1 gene...
AbstractHigh levels of choline kinase (ChoK) expression and choline phospholipid metabolites are oft...
<p>(A) RT-PCR analysis of Chk-α and β in MCF-7 and MCF-7/TAM cells. The level of Chk-α mRNA was high...
Choline kinase (Chok) is an enzyme found in eukaryotes and Gram-positive bacteria. Chok catalyzes th...
Choline metabolites are elevated in breast cancer, decrease in response to effective therapy and are...
Histone deacetylase (HDAC) inhibitors have emerged as effective antineoplastic agents in the clinic....
Histone deacetylase (HDAC) inhibitors have emerged as effective antineoplastic agents in the clinic....
<p><b>A)</b> and <b>B)</b><i>In vitro</i> ChoK activity of cell-free extracts from transfected cells...
Aberrant choline metabolism, characterized by an increase in total choline-containing compounds, pho...
<p>Choline kinase isoforms were expressed alone or in combination with the indicated Ras and Rho GTP...
Treatment of [3H]-choline- or [14C]-ethanolamine-labelled undifferentiated bipolar and differentiate...
Choline kinase beta (CKβ) is one of the CK isozymes involved in the biosynthesis of phosphatidylchol...
Phosphatidylcholine metabolism was investigated in Nb 2 node rat lymphoma, a cell line which is depe...
The glycerophospholipid phosphatidylcholine is the most abundant phospholipid species of eukaryotic ...
We studied the effect of choline depletion on the biosynthesis of phosphatidylcholine (PC) and the d...
<p>HEK293T cells were transfected with eukaryotic expression vectors of human ChoKα1 and ChoKβ1 gene...
AbstractHigh levels of choline kinase (ChoK) expression and choline phospholipid metabolites are oft...
<p>(A) RT-PCR analysis of Chk-α and β in MCF-7 and MCF-7/TAM cells. The level of Chk-α mRNA was high...
Choline kinase (Chok) is an enzyme found in eukaryotes and Gram-positive bacteria. Chok catalyzes th...
Choline metabolites are elevated in breast cancer, decrease in response to effective therapy and are...
Histone deacetylase (HDAC) inhibitors have emerged as effective antineoplastic agents in the clinic....
Histone deacetylase (HDAC) inhibitors have emerged as effective antineoplastic agents in the clinic....
<p><b>A)</b> and <b>B)</b><i>In vitro</i> ChoK activity of cell-free extracts from transfected cells...
Aberrant choline metabolism, characterized by an increase in total choline-containing compounds, pho...
<p>Choline kinase isoforms were expressed alone or in combination with the indicated Ras and Rho GTP...
Treatment of [3H]-choline- or [14C]-ethanolamine-labelled undifferentiated bipolar and differentiate...
Choline kinase beta (CKβ) is one of the CK isozymes involved in the biosynthesis of phosphatidylchol...
Phosphatidylcholine metabolism was investigated in Nb 2 node rat lymphoma, a cell line which is depe...
The glycerophospholipid phosphatidylcholine is the most abundant phospholipid species of eukaryotic ...
We studied the effect of choline depletion on the biosynthesis of phosphatidylcholine (PC) and the d...
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