Inhibition of spheroid growth.

<p>a) Sequential images of the same HeLa and HT29 spheroids following treatment with BCM+DTX at a concentration of 20 ng/mL. Bars represent 100 µm. Growth inhibition of HeLa (b,c) and HT29 (d,e) MCTS by BCM+DTX and <b>Taxotere</b>® at concentrations of 2, 20 and 200 ng/mL. Cells were re-treated after two weeks (arrow). Box represents expanded region of plots b) and d). Data is expressed as the mean volume of six spheroids (n = 6) ± SD. “*” represents a significant difference between BCM 20 and TAX 20, p<0.05.