<p>The injection of nanoprodrug either IV or IP results in similar accumulation in animals with TBI, while normal animals given nanoprodrug and TBI animals do not show any background flourescence. Brains are oriented with the rostral portion toward the top of the image.</p
<p>Male mice were injected i.p. with 60 mg/kg TAT- UCH-L1 fusion protein (TAT) or vehicle (Veh) 1 ho...
<p>(A) Experimental design for the <i>in vivo</i> experiments. Before entering the study, mice were ...
<p>Sections obtained from TBI-induced WT mice demonstrate positive staining for nitrotyrosine (A) ma...
<p>This schematic illustrates the difference between healthy brain and injured brain in terms of the...
TEG, contains a tetra ethylene glycol (TEG) spacer consisting of biodegradable ester bonds. The biod...
Nanoparticle (NP) based therapeutic and theranostic agents have been developed for various diseases,...
<p>MNCs were labeled with Q-tracker(green). These animals had undergone stroke, 24 hrs later were in...
Traumatic brain injury (TBI) is an enormous public health problem, with 1.7 million new cases of TBI...
Introduction: We have recently shown that intracerebral delivery of an anti-VEGF monoclonal antibody...
<p>Comparison of brain uptake of three radioiodinated pyridyl benzofuran derivatives in normal mice....
<p>Representative sections of Fluoro-Jade B staining in different regions of hippocampus of control ...
<p>(<b>A</b>) Representative cresyl violet-stained brain sections of vehicle- and 40 mg·kg<sup>−1</s...
<p>(A) Illustration of a coronal slice of the mouse brain representing the areas used to evaluate ne...
<p>(<b>A</b>) P2X7−/− mice exhibited a significant reduction in brain water content, as compared to ...
Given the extensive application of carbon nanotubes (CNTs) in biomedical fields, there is increasing...
<p>Male mice were injected i.p. with 60 mg/kg TAT- UCH-L1 fusion protein (TAT) or vehicle (Veh) 1 ho...
<p>(A) Experimental design for the <i>in vivo</i> experiments. Before entering the study, mice were ...
<p>Sections obtained from TBI-induced WT mice demonstrate positive staining for nitrotyrosine (A) ma...
<p>This schematic illustrates the difference between healthy brain and injured brain in terms of the...
TEG, contains a tetra ethylene glycol (TEG) spacer consisting of biodegradable ester bonds. The biod...
Nanoparticle (NP) based therapeutic and theranostic agents have been developed for various diseases,...
<p>MNCs were labeled with Q-tracker(green). These animals had undergone stroke, 24 hrs later were in...
Traumatic brain injury (TBI) is an enormous public health problem, with 1.7 million new cases of TBI...
Introduction: We have recently shown that intracerebral delivery of an anti-VEGF monoclonal antibody...
<p>Comparison of brain uptake of three radioiodinated pyridyl benzofuran derivatives in normal mice....
<p>Representative sections of Fluoro-Jade B staining in different regions of hippocampus of control ...
<p>(<b>A</b>) Representative cresyl violet-stained brain sections of vehicle- and 40 mg·kg<sup>−1</s...
<p>(A) Illustration of a coronal slice of the mouse brain representing the areas used to evaluate ne...
<p>(<b>A</b>) P2X7−/− mice exhibited a significant reduction in brain water content, as compared to ...
Given the extensive application of carbon nanotubes (CNTs) in biomedical fields, there is increasing...
<p>Male mice were injected i.p. with 60 mg/kg TAT- UCH-L1 fusion protein (TAT) or vehicle (Veh) 1 ho...
<p>(A) Experimental design for the <i>in vivo</i> experiments. Before entering the study, mice were ...
<p>Sections obtained from TBI-induced WT mice demonstrate positive staining for nitrotyrosine (A) ma...