Disorganized vascular structures at the region of nanoprodrug uptake.

<p>Representative images from two brains showing nanoprodrug uptake on the left column and CD31 staining of vascular endothelial cells on the right. Outside of the TBI region, vascular structures exist in normal tubular arrangements, but these are disorganized within the region of injury. The nuclei are stained with DAPI are displayed in blue. <i>Scale bar,</i> 50 <i>µ</i>m.