Validation of CLI signal originating from BAT (n = 3).

<p>(a–b) Biodistribution of ¹⁸F-FDG in dissected tissues. Radioactivity quantifications (a) and CLI readings (b). Both methods indicated that BAT had the highest ¹⁸F-FDG uptake. (c–d) Representative images of mice before (c, left) and after (c, right) BAT removal; (d) Quantification indicated that >85% CLI originated from BAT.