<p>Primary human (<b>A</b>) MDM or (<b>B</b>) AM were infected with <i>MTB</i> H37Rv and after 1 hr, 24 hrs, 4 days, or 8 days of infection, supernatants were assayed for TNFα by ELISA and IFNγ by electrochemiluminescence. Data shown are estimated means with standard error bars from linear mixed model fits, based on seven independent experiments (MDM) or nine independent experiments (AM). *p<0.05 and **p<0.01 for cytokine expression in macrophages infected with <i>MTB</i> alone (closed circles) vs. <i>MTB</i>+BAY (closed squares). Control = (open circles) and BAY = (open squares).</p
<p>Macrophages were infected with H37Rv, a laboratory strain of <i>M</i>.<i>tb</i>, with multiplicit...
<p>(<b>A</b>) Peritoneal macrophages isolated from <i>Hri</i> +/+ and -/- mice were infected <i>in v...
<p>Groups of BALB/c mice (4 mice per group) were inoculated with either 3×10<sup>5</sup> or 3×10<sup...
<p>(A) Experimental setup: ANA-I cells were treated for 5 days with Zymosan and IFNγ in the presence...
<p>(<b>A</b>) THP-1 cells were infected with <i>MTB</i> H37Rv for 4 and 8 days with or without BAY, ...
Cytokine concentrations in cell culture supernatants were determined by ELISA for PBMCs infected wit...
<p>Human MDMs were treated with siRNA against target genes or a non-targeted control before infectio...
<p>(<b>A</b>) Relative protein and transcript levels of TNF, IFNγ and MCP-1 in lysates from wild typ...
<p>(A) IFNγ/TNFα treatment inhibits EBOV infection of BALB/c peritoneal macrophages. Cultures mainta...
<p>mDC generated from wild type and DKO mice were (A) stimulated with 50 µg/ml of poly(I∶C) or 2 µg/...
<p>(A) THP-1 cells, (B) MDM, or (C) AM were pretreated with 0.1% (v/v) DMSO (open squares) or 5 µM B...
<p>MDMs were treated with IFN-γ (100 ng/ml), TNF-α (20 ng/ml), IL1-β (20 ng/ml), IL-6 (20 ng/ml) or ...
<p>(A) BMDM generated from WT (black bars), TLR2<sup>−/−</sup> (grey bars) or TLR4<sup>−/−</sup> (wh...
Cytokine concentrations in cell culture supernatants were determined by ELISA at days 0, 3, 5 and 8 ...
<p>24 hours prior to infection mice were injected with 100 μg of anti NK1.1 antibody i.p. mice were ...
<p>Macrophages were infected with H37Rv, a laboratory strain of <i>M</i>.<i>tb</i>, with multiplicit...
<p>(<b>A</b>) Peritoneal macrophages isolated from <i>Hri</i> +/+ and -/- mice were infected <i>in v...
<p>Groups of BALB/c mice (4 mice per group) were inoculated with either 3×10<sup>5</sup> or 3×10<sup...
<p>(A) Experimental setup: ANA-I cells were treated for 5 days with Zymosan and IFNγ in the presence...
<p>(<b>A</b>) THP-1 cells were infected with <i>MTB</i> H37Rv for 4 and 8 days with or without BAY, ...
Cytokine concentrations in cell culture supernatants were determined by ELISA for PBMCs infected wit...
<p>Human MDMs were treated with siRNA against target genes or a non-targeted control before infectio...
<p>(<b>A</b>) Relative protein and transcript levels of TNF, IFNγ and MCP-1 in lysates from wild typ...
<p>(A) IFNγ/TNFα treatment inhibits EBOV infection of BALB/c peritoneal macrophages. Cultures mainta...
<p>mDC generated from wild type and DKO mice were (A) stimulated with 50 µg/ml of poly(I∶C) or 2 µg/...
<p>(A) THP-1 cells, (B) MDM, or (C) AM were pretreated with 0.1% (v/v) DMSO (open squares) or 5 µM B...
<p>MDMs were treated with IFN-γ (100 ng/ml), TNF-α (20 ng/ml), IL1-β (20 ng/ml), IL-6 (20 ng/ml) or ...
<p>(A) BMDM generated from WT (black bars), TLR2<sup>−/−</sup> (grey bars) or TLR4<sup>−/−</sup> (wh...
Cytokine concentrations in cell culture supernatants were determined by ELISA at days 0, 3, 5 and 8 ...
<p>24 hours prior to infection mice were injected with 100 μg of anti NK1.1 antibody i.p. mice were ...
<p>Macrophages were infected with H37Rv, a laboratory strain of <i>M</i>.<i>tb</i>, with multiplicit...
<p>(<b>A</b>) Peritoneal macrophages isolated from <i>Hri</i> +/+ and -/- mice were infected <i>in v...
<p>Groups of BALB/c mice (4 mice per group) were inoculated with either 3×10<sup>5</sup> or 3×10<sup...