ROI seed based functional connectivity maps in the midbrain for 3-D sequences.

<p>Functional connectivity maps for FFE (Panel A) and PRESTO (Panel B) scans in a representative participant. An uncorrected voxel level threshold of p<10⁻⁶ (cluster size = 30 voxels) was used for the FFE scans and an uncorrected voxel level threshold of p<10⁻¹⁰ (cluster size = 30 voxels) was used for the PRESTO scans. Seed regions of interest in the midbrain include left Substantia Nigra (L_SN), right Substantia Nigra (R_SN), left Ventral Tegmental Area (L_VTA), and right Ventral Tegmental Area (R_VTA). Color bar represents T-statistic. FFE voxel size = 1.33 mm³ and PRESTO voxel size = 2.5 mm³. Axial midbrain slice sections are displayed at the level of the superior colliculus. N = 6 in each sequence type. <b>L</b> denotes the left side of the brain and <b>P</b> denotes the posterior portion of the brain. Data were motion corrected, put through RETROICOR, and band-pass filtered between 0.01 and 0.1 Hz. Robust bilateral spatial distribution of functional connectivity was observed in most ROIs.