Effect of conditioned media from hUC-MSCs on the Wnt signaling pathway of HCCC-9810 cells.

<p>Immunoblot analysis showed that the treatment of HCCC-9810 cells with 50% conditioned media from hUC-MSCs cultures led to the down-regulation of β-catenin, c-Myc, and cyclin-D1 expression, while the levels of these proteins in control groups was unchanged (A). After treatment for 48 h, 50% conditioned media from hUC-MSCs cultures prevented nuclear translocation of β-catenin in HCCC-9810 cells (B). Results shown are representative of three independent experiments.