Ching001 induces M-phase arrest and DNA damage.

<p>(<b>A</b>) Western blot analyses of mitosis-related proteins after 1 µM Ching001 treatment for indicated times in lung cancer cell lines. (<b>B</b>) Dysregulation of M-phase cell cycle induced by Ching001. Lung cancer cell lines were analyzed with survivin (green), aurora B (red), and DAPI (blue) after 1 µM Ching001 treatment for 24 h. DMSO was used as solvent control. Scale bars: 30 µm.