Acetate induces cell proliferation arrest in a concentration & pH dependent manner.

<p>A: Number of m-ICcl2 per well after incubation at different pH with 20 mM of SCFA. Number represent cell counts (x10⁵) per well. B-C: qRT-PCR of cyclin D1 (B) and cyclin E1 (C) gene expression after incubation of m-ICcl2 with or without 20 mM acetate or lactate at different pHs. qRT-PCR was analyzed by the dδCt method using m-ICcl2 alone and GAPDH as reference.