<p>(<b>A</b>) Representative current traces show responses to the maximal GABA and taurine concentrations at different receptor types. For two representative receptor types (marked with symbols) concentration-response plots for GABA (filled symbols) and taurine (open symbols) are shown in (<b>B</b>) and (<b>C</b>). Data obtained in corresponding wild type receptors (γ<sub>2</sub> instead of γ<sub>2F77I</sub>) are plotted in red.</p
The aim of this study was to determine whether the knockout of the taurine-transporter gene in the m...
1. The effects of Zn2+ on glycine receptor (GlyR) currents were analysed in Xenopus oocytes and huma...
GABAA receptor function can be conceptually divided into interactions between ligand and receptor (b...
<p>(<b>A</b>) Whole-cell voltage-clamp recordings (V<sub>h</sub> = −50 mV) from adult WT or KI mouse...
<p>(<b>A and B)</b> Representative current traces (comparison of taurine (600 mM) - and GABA (0.3–3 ...
<p>GABA I <sub>max</sub> = 1; Responses to different taurine concentrations relative to I GABA max w...
<p>Note that gating by taurine of γ<sub>2</sub> subunit containing GABA<sub>A</sub> receptors is sig...
Taurine is a semi-essential sulfonic acid found at high concentrations in plasma and mammalian tissu...
<div><p>Taurine is a semi-essential sulfonic acid found at high concentrations in plasma and mammali...
Taurine is a semi-essential sulfonic acid found at high concentrations in plasma and mammalian tissu...
<p><b>Panel A)</b> Data are reproduced from Guitchounts et al <a href="http://www.plosone.org/articl...
<p>Each panel shows a cumulative distribution for the mean parameter values for receptors with diffe...
<p><b>Panel</b><b>A</b> shows sample traces of data for wild-type receptors and receptors containing...
Taurine activates and modulates GABA receptors in vivo as well as those expressed in heterologous sy...
<p><b>A.</b> GABA-evoked currents, in response to maximal concentrations and concentrations around E...
The aim of this study was to determine whether the knockout of the taurine-transporter gene in the m...
1. The effects of Zn2+ on glycine receptor (GlyR) currents were analysed in Xenopus oocytes and huma...
GABAA receptor function can be conceptually divided into interactions between ligand and receptor (b...
<p>(<b>A</b>) Whole-cell voltage-clamp recordings (V<sub>h</sub> = −50 mV) from adult WT or KI mouse...
<p>(<b>A and B)</b> Representative current traces (comparison of taurine (600 mM) - and GABA (0.3–3 ...
<p>GABA I <sub>max</sub> = 1; Responses to different taurine concentrations relative to I GABA max w...
<p>Note that gating by taurine of γ<sub>2</sub> subunit containing GABA<sub>A</sub> receptors is sig...
Taurine is a semi-essential sulfonic acid found at high concentrations in plasma and mammalian tissu...
<div><p>Taurine is a semi-essential sulfonic acid found at high concentrations in plasma and mammali...
Taurine is a semi-essential sulfonic acid found at high concentrations in plasma and mammalian tissu...
<p><b>Panel A)</b> Data are reproduced from Guitchounts et al <a href="http://www.plosone.org/articl...
<p>Each panel shows a cumulative distribution for the mean parameter values for receptors with diffe...
<p><b>Panel</b><b>A</b> shows sample traces of data for wild-type receptors and receptors containing...
Taurine activates and modulates GABA receptors in vivo as well as those expressed in heterologous sy...
<p><b>A.</b> GABA-evoked currents, in response to maximal concentrations and concentrations around E...
The aim of this study was to determine whether the knockout of the taurine-transporter gene in the m...
1. The effects of Zn2+ on glycine receptor (GlyR) currents were analysed in Xenopus oocytes and huma...
GABAA receptor function can be conceptually divided into interactions between ligand and receptor (b...