Similarity clustering and STRING analysis of the regeneration-specific genes identified by two-way ANOVA analysis.

<p>A. Heat map of 150 probes (with 93 different human homolog assignments) that are up-regulated in regenerating but not in lateral wound samples shows a diversity of expression kinetics. log₂ values of standard scores of normalized signal are shown. Up-regulation is indicated by red, down-regulation by blue color. B. STRING analysis of the gene set showing only high confidence functional connections (confidence score ≥0.7). Five functional networks are identified: response to oxidative and cellular stress (yellow), ribonucleoprotein network (red), chromatin-remodeling (blue), epithelial cluster (green), development cluster (pink). Large balls represent gene families where a structure is available. Six identifiers were not recognized by STRING 9.0 interface and therefore 87 candidates were considered). See also Table S1, and Figure S5.