One-Pot and Regiospecific Synthesis of 2,3-Disubstituted Indoles from 2‑Bromoanilides via Consecutive Palladium-Catalyzed Sonogashira Coupling, Amidopalladation, and Reductive Elimination

Bruce Z. Lu (1479184)
Han-Xun Wei (1754674)
Yongda Zhang (1392793)
Wenyi Zhao (1754689)
Marine Dufour (1963564)
Guisheng Li (1552309)
Vittorio Farina (1528342)
Chris H. Senanayake (1560043)

Publication date

May 2013

DOI

Abstract

A practical one-pot and regiospecific three-component process for the synthesis of 2,3-disubstituted indoles from 2-bromoanilides was developed via consecutive palladium-catalyzed Sonogashira coupling, amidopalladation, and reductive elimination

Extracted data

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One-Pot and Regiospecific Synthesis of 2,3-Disubstituted Indoles from 2‑Bromoanilides via Consecutive Palladium-Catalyzed Sonogashira Coupling, Amidopalladation, and Reductive Elimination

Abstract

Extracted data

One-Pot and Regiospecific Synthesis of 2,3-Disubstituted Indoles from 2‑Bromoanilides via Consecutive Palladium-Catalyzed Sonogashira Coupling, Amidopalladation, and Reductive Elimination

Abstract

Extracted data

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