The effects of PTE on proteins in the Notch1 signaling pathway and the mitochondrial apoptotic pathway in lung adenocarcinoma cells treated for 24 h.

<p>(A) Representative Western blot results are shown. The PTE treatment increased the expression levels of NICD, Hes1, Nicastrin, Presenilin-1, Bax and Cytochrome c. (B) Representative images of Notch1 immunofluorescence are shown (×400). (C) Representative images of Hes1 immunofluorescence are shown (×400). The results are expressed as the mean ± SEM, n = 6. **P<0.01 compared with the control group, ^##P<0.01 compared with the PTE 1.5 µM group, ^$$P<0.01 compared with the PTE 3 µM group. PTE, pterostilbene.