Soluble mediator secretion by normal and OA synovial tissue explants (STEs) with or without IL-1α.
- Lobke M. Gierman (409707)
- Benno van El (409708)
- Frits van der Ham (409709)
- Angela Koudijs (409710)
- Reinout Stoop (409711)
- Jan H. Verheijen (409712)
- Margreet Kloppenburg (174774)
- Gerjo J. V. M. van Osch (229421)
- Vedrana Stojanovic-Susulic (123556)
- Tom W. J. Huizinga (94591)
- Anne-Marie Zuurmond (409713)
Publication date
May 2013
DOIAbstract
<p>Graphs demonstrate all soluble mediators which were significantly (p<0.01) different between <b>A.</b> normal (black bars) and OA (grey bars) STEs and <b>B.</b> normal and OA STEs under pro-inflammatory (IL-1α) conditions. Data were obtained from pooled supernatants representing the average of 6 STEs per donor and the production in a time period of 7 days. Data are plotted on a log scale. Bars indicate mean concentration (pg/ml culture medium) ± SD.</p
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