Olfactory deficit reduced the expression level of GSK3β in the OB.

<p>A: T-GSK3β was widely expressed in the mouse OB, including the mitral cells and granule cells. B: The T-GSK3β signal was significantly decreased in the OBs of CNGX mice. C: The T-GSK3β signal was decreased one month after ZnSO₄ irrigation. D: The T-GSK3β expression level in OB was partially recovered four months after ZnSO₄ irrigation. (A–D: white arrow, mitral cell layer; yellow arrow, granular cell layer). E & F: Compared to the signal at one month following ZnSO₄ irrigation, Syn in the OB was stronger at four months post-treatment (E–F: white arrow, glomerulus). Syn: synaptophysin; Scale bar, A–D, 100 µm; E–F, 50 µm.