Inhibitory effects of <b>1</b>–<b>4</b> on superoxide anion generation and elastase release by human neutrophils in response to FMLP/CB.

a<p>Concentration necessary for 50% inhibition. Results are presented as the mean ± S.D. (n = 3).</p>***<p>P<0.001 compared with the control value.</p>b<p>Alone induced superoxide generation by human neutrophils.</p>c<p>Sorafenib, a tyrosine kinase inhibitor, was used as a positive control.