Increased ROS is required for homocysteine-induced apoptosis of BMSCs.
- Benzhi Cai (410524)
- Xingda Li (410525)
- Yang Wang (5921)
- Yanju Liu (410526)
- Fan Yang (1413)
- Hongyang Chen (410527)
- Kun Yin (180756)
- Xueying Tan (410528)
- Jiuxin Zhu (410529)
- Zhenwei Pan (296083)
- Baoqiu Wang (410530)
- Yanjie Lu (219266)
Publication date
May 2013
DOIAbstract
<p>(a) DMTU and NAC attenuated the increase of ROS level by homocysteine in BMSCs. (b) Effects of DMTU and NAC on the apoptotic appearance of BMSCs. The inhibition of ROS with DMTU and NAC abolished the apoptosis of BMSCs induced by homocysteine. (c) Homocysteine-induced depolarization of mitochondrial membrane potential was also effectively reserved by DMTU and NAC in BMSCs.</p
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