C5aR and C5L2 expression in adipose, muscle and liver of mice.

<p>C5aR mRNA expression for WT CHOW (open bars) and WT diet-induced obesity (DIO) (checkered bars) for (A) gonadal adipose tissue, (B) quadriceps muscle, and (C) liver were measured. C5L2 mRNA expression for WT CHOW (open bars), WT DIO (checkered bars), KO CHOW (black bars) and KO DIO (striped bars) for (D) gonadal adipose tissue, (E) quadriceps muscle, and (F) liver were evaluated. Results are expressed as means ± SEM; n = 9–12 per group. Statistical differences were determined by t-test, for C5aRKO vs WT on their respective diets where *P<0.05, **P<0.001 and ***P<0.0001.