Effect of the injection of PC61 mAb on the Treg cells of ZIGI mice.

<p>Mice (6 animals per group) were injected intraperitoneally with 200 μg of IgG1 mAb (a, c) or 200 μg of purified anti-CD25 mAb (PC61) (b, d) on day −2. Zymosan was administered intraperitoneally on day 0. The spleen cells were collected on day 2 and day 5. The numbers indicate the percentage of CD4⁺CD25⁺cells within the CD4⁺population and the percentage of Foxp3⁺cells within the CD4⁺population. The values show the means ± SEM. **<i>P</i><0.01 compared withthe ZYM and the IgG1+ZYM groups.