Effects of fluoxetine on monoaminergic synaptic modulation in corticosterone-treated mice.

<p>(A) Effects of fluoxetine on serotonin-induced synaptic potentiation. CORT effect: <i>P</i> = 0.0049, CORT×FLX: <i>P</i> = 0.0489 (<i>n</i> = 5 to 7). (B) Facilitated effects of fluoxetine on synaptic potentiation induced by dopamine (10 µM). CORT effect: <i>P</i> = 0.0006, FLX effect: <i>P</i> = 0.0004, CORT×FLX: <i>P</i> = 0.0336 (<i>n</i> = 6 to 7). ***<i>P</i><0.001 compared with CNT/CORT. The bar graph at right includes the results from slices pretreated with SCH23390 (<i>n</i> = 4 slices each). (C) Facilitated effects of fluoxetine on synaptic potentiation induced by SKF81297 (100 nM). CORT effect: <i>P</i><0.0001, FLX effect: <i>P</i> = 0.0004, CORT×FLX: <i>P</i> = 0.0011 (<i>n</i> = 3 to 4 slices). ***<i>P</i><0.001 compared with CNT/CORT.