Assessment of new bone regeneration in the necrotic area.

<p>Representative histological photomicrograph of the necrotic area of the femoral head showed massive trabecular tissue had formed in Group I and there were few granulation tissue (A). In Group II, there were fewer trabecular tissue and more granulation tissue as compared to that in Group I (B). In Group III, a few osteocyte filled lacunae were replaced by empty lacunae. The marrow fat cells were increased compared to that of Group I and II (C). In Group IV, there were rarely any trabecular tissue, and a lot of empty lacunae were observed (D). Scale bars = 50 um. Arrowheads indicate empty lacunae. (E) Histomorphometric analysis showed new bone density in Group I was significantly more than that of the other three groups (p<0.01).